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Bidirectional interactions between indomethacin and the murine intestinal microbiota

The vertebrate gut microbiota have been implicated in the metabolism of xenobiotic compounds, motivating studies of microbe-driven metabolism of clinically important drugs. Here, we studied interactions between the microbiota and indomethacin, a nonsteroidal anti-inflammatory drug (NSAID) that inhib...

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Detalhes bibliográficos
Publicado no:eLife
Main Authors: Liang, Xue, Bittinger, Kyle, Li, Xuanwen, Abernethy, Darrell R, Bushman, Frederic D, FitzGerald, Garret A
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4755745/
https://ncbi.nlm.nih.gov/pubmed/26701907
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.08973
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