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Protocols for Analyzing the Role of Paneth Cells in Regenerating the Murine Intestine using Conditional Cre-lox Mouse Models

The epithelial surface of the mammalian intestine is a dynamic tissue that renews every 3 - 7 days. Understanding this renewal process identified a population of rapidly cycling intestinal stem cells (ISCs) characterized by their expression of the Lgr5 gene. These are supported by a quiescent stem c...

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Detalles Bibliográficos
Publicado en:J Vis Exp
Main Authors: Parry, Lee, Young, Madeleine, El Marjou, Fatima, Clarke, Alan Richard
Formato: Artigo
Idioma:Inglês
Publicado: MyJove Corporation 2015
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4755722/
https://ncbi.nlm.nih.gov/pubmed/26649885
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3791/53429
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