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Jagn1 Is Induced in Response to ER Stress and Regulates Proinsulin Biosynthesis
The Jagn1 protein was indentified in a SILAC proteomic screen of proteins that are increased in insulinoma cells expressing a folding-deficient proinsulin. Jagn1 mRNA was detected in primary rodent islets and in insulinoma cell lines and the levels were increased in response to ER stress. The functi...
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| 出版年: | PLoS One |
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| 主要な著者: | , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Public Library of Science
2016
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4755616/ https://ncbi.nlm.nih.gov/pubmed/26882284 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0149177 |
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