SHP-1 Deficient Mast Cells Are Hyperresponsive to Stimulation and Critical in Initiating Allergic Inflammation in the Lung

Phosphatase Src homology region 2 domain-containing phosphatase 1 (SHP-1)-deficient mice display an allergic asthma phenotype that is largely IL-13 and STAT6 dependent. The cell types responsible for the Th2 phenotype have not been identified. We hypothesized that SHP-1 deficiency leads to mast cell...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:J Immunol
Päätekijät: Zhang, Li, Oh, Sun Young, Wu, Xinxing, Oh, Min Hee, Wu, Fan, Schroeder, John T., Takemoto, Clifford M., Zheng, Tao, Zhu, Zhou
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2009
Aiheet:
Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4755278/
https://ncbi.nlm.nih.gov/pubmed/20042576
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0901972
Tagit: Lisää tagi
Ei tageja, Lisää ensimmäinen tagi!

Samankaltaisia teoksia