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Comparison of Exome and Genome Sequencing Technologies for the Complete Capture of Protein‐Coding Regions

For next‐generation sequencing technologies, sufficient base‐pair coverage is the foremost requirement for the reliable detection of genomic variants. We investigated whether whole‐genome sequencing (WGS) platforms offer improved coverage of coding regions compared with whole‐exome sequencing (WES)...

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Detalhes bibliográficos
Publicado no:Hum Mutat
Main Authors: Lelieveld, Stefan H., Spielmann, Malte, Mundlos, Stefan, Veltman, Joris A., Gilissen, Christian
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4755152/
https://ncbi.nlm.nih.gov/pubmed/25973577
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/humu.22813
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