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Estimation of expectedness: Predictive accuracy of standard therapy outcomes in randomized phase 3 studies in epithelial ovarian cancer

BACKGROUND: The anticipated clinical outcome of the standard/control arm is an important parameter in the design of randomized phase 3 (RP3) trials to properly calculate sample size, power, and study duration. Changing patterns of care or variation in the study population enrolled may lead to a devi...

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Detalhes bibliográficos
Publicado no:Cancer
Main Authors: Castonguay, Vincent, Wilson, Michelle K., Diaz‐Padilla, Ivan, Wang, Lisa, Oza, Amit M.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4755141/
https://ncbi.nlm.nih.gov/pubmed/25278038
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cncr.29030
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