Fluoxetine Protection in Decompression Sickness in Mice is Enhanced by Blocking TREK-1 Potassium Channel with the “spadin” Antidepressant

In mice, disseminated coagulation, inflammation, and ischemia induce neurological damage that can lead to death. These symptoms result from circulating bubbles generated by a pathogenic decompression. Acute fluoxetine treatment or the presence of the TREK-1 potassium channel increases the survival r...

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Udgivet i:Front Physiol
Main Authors: Vallée, Nicolas, Lambrechts, Kate, De Maistre, Sébastien, Royal, Perrine, Mazella, Jean, Borsotto, Marc, Heurteaux, Catherine, Abraini, Jacques, Risso, Jean-Jacques, Blatteau, Jean-Eric
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2016
Fag:
Physiology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4755105/
https://ncbi.nlm.nih.gov/pubmed/26909044
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2016.00042
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