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Atorvastatin (Lipitor) attenuates the effects of aspirin on pancreatic cancerogenesis and the chemotherapeutic efficacy of gemcitabine on pancreatic cancer by promoting M2 polarized tumor associated macrophages

BACKGROUND: Interactions of inflammatory cells with pancreatic cancer cells play crucial roles in pancreatic cancer, however the dynamic changes of inflammatory cell populations in pancreatic cancerogensis and after chemotherapy have not been well eclucidated. The combinational use of aspirin and at...

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Bibliografiske detaljer
Udgivet i:J Exp Clin Cancer Res
Main Authors: Liu, Qiaofei, Li, Yuan, Niu, Zheyu, Zong, Yi, Wang, Mengyi, Yao, Lutian, Lu, Zhaohui, Liao, Quan, Zhao, Yupei
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4754966/
https://ncbi.nlm.nih.gov/pubmed/26879926
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13046-016-0304-4
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