Higher plasma levels of complement C3a, C4a and C5a increase the risk of subretinal fibrosis in neovascular age-related macular degeneration: Complement activation in AMD

BACKGROUND: The aim of this study was to investigate the plasma levels of complement C3a, C4a, and C5a in different types of neovascular age-related macular degeneration (nAMD) and whether the levels were related to patients’ responsiveness to anti-VEGF therapy. RESULTS: Ninety-six nAMD patients (in...

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Bibliografiske detaljer
Udgivet i:Immun Ageing
Main Authors: Lechner, Judith, Chen, Mei, Hogg, Ruth E., Toth, Levente, Silvestri, Giuliana, Chakravarthy, Usha, Xu, Heping
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2016
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4754842/
https://ncbi.nlm.nih.gov/pubmed/26884800
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12979-016-0060-5
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