Paclitaxel and the dietary flavonoid fisetin: a synergistic combination that induces mitotic catastrophe and autophagic cell death in A549 non-small cell lung cancer cells

BACKGROUND: The use of the dietary polyphenols as chemosensitizing agents to enhance the efficacy of conventional cytostatic drugs has recently gained the attention of scientists and clinicians as a plausible approach for overcoming the limitations of chemotherapy (e.g. drug resistance and cytotoxic...

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Publicado en:Cancer Cell Int
Autores principales: Klimaszewska-Wisniewska, Anna, Halas-Wisniewska, Marta, Tadrowski, Tadeusz, Gagat, Maciej, Grzanka, Dariusz, Grzanka, Alina
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2016
Materias:
Primary Research
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4754822/
https://ncbi.nlm.nih.gov/pubmed/26884726
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12935-016-0288-3
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