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The intracellular domain of the Frazzled/DCC receptor is a transcription factor required for commissural axon guidance
In commissural neurons of Drosophila, the conserved Frazzled (Fra)/Deleted in Colorectal Cancer (DCC) receptor promotes midline axon crossing by signaling locally in response to Netrin and by inducing transcription of commissureless (comm), an antagonist of Slit-Roundabout midline repulsion, through...
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| Publicado no: | Neuron |
|---|---|
| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4754793/ https://ncbi.nlm.nih.gov/pubmed/26291159 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2015.08.006 |
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