Randomized, Double-Blind, Placebo-Controlled Trial of Thiamine as a Metabolic Resuscitator in Septic Shock: A Pilot Study

OBJECTIVE: To determine if intravenous thiamine would reduce lactate in patients with septic shock. DESIGN: Randomized, double-blind, placebo-controlled trial. SETTING: Two US hospitals. PATIENTS: Adult patients with septic shock and elevated (> 3 mmol/L) lactate between 2010 and 2014. INTERVENTI...

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Vydáno v:Crit Care Med
Hlavní autoři: Donnino, Michael W., Andersen, Lars W., Chase, Maureen, Berg, Katherine M., Tidswell, Mark, Giberson, Tyler, Wolfe, Richard, Moskowitz, Ari, Smithline, Howard, Ngo, Long, Cocchi, Michael N.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2016
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4754670/
https://ncbi.nlm.nih.gov/pubmed/26771781
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/CCM.0000000000001572
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