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Epstein–Barr virus‐induced gene 3 suppresses T helper type 1, type 17 and type 2 immune responses after Trypanosoma cruzi infection and inhibits parasite replication by interfering with alternative macrophage activation

The Epstein–Barr virus‐induced gene 3 (EBI3) is a member of the interleukin‐12 (IL)‐12) family structurally related to the subunit p40 of IL‐12 and forms a heterodimer either with the p28 subunit to build IL‐27 or with p35 to form IL‐35. Interleukin‐27 is secreted by antigen‐presenting cells whereas...

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Dades bibliogràfiques
Publicat a:Immunology
Autors principals: Böhme, Julia, Roßnagel, Caroline, Jacobs, Thomas, Behrends, Jochen, Hölscher, Christoph, Erdmann, Hanna
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4754611/
https://ncbi.nlm.nih.gov/pubmed/26694585
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/imm.12565
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