Localized Delivery of Low-Density Lipoprotein Docosahexaenoic Acid Nanoparticles to the Rat Brain using Focused Ultrasound

Focused ultrasound exposures in the presence of microbubbles can achieve transient, non-invasive, and localized blood-brain barrier (BBB) opening, offering a method for targeted delivery of therapeutic agents into the brain. Low-density lipoprotein (LDL) nanoparticles reconstituted with docosahexaen...

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Pubblicato in:Biomaterials
Autori principali: Mulik, Rohit S., Bing, Chenchen, Ladouceur-Wodzak, Michelle, Munaweera, Imalka, Chopra, Rajiv, Corbin, Ian R.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2016
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4754139/
https://ncbi.nlm.nih.gov/pubmed/26790145
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biomaterials.2016.01.021
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