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CaMKII regulates proteasome phosphorylation and activity and promotes memory destabilization following retrieval

Numerous studies have suggested that memories “destabilize” and require de novo protein synthesis in order to reconsolidate following retrieval, but very little is known about how this destabilization process is regulated. Recently, ubiquitin-proteasome mediated protein degradation has been identifi...

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Détails bibliographiques
Publié dans:Neurobiol Learn Mem
Auteurs principaux: Jarome, Timothy J., Ferrara, Nicole C., Kwapis, Janine L., Helmstetter, Fred J.
Format: Artigo
Langue:Inglês
Publié: 2016
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4754128/
https://ncbi.nlm.nih.gov/pubmed/26779588
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nlm.2016.01.001
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