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Exome Sequencing of families with Histiocytoid Cardiomyopathy reveals a Complex I Mitochondrial Etiology with NDUFB11 Mutation

Histiocytoid cardiomyopathy (Histiocytoid CM) is a rare form of cardiomyopathy observed predominantly in newborn females that is fatal unless treated early in life. We have performed whole exome sequencing on five parent-proband trios and identified nuclear-encoded mitochondrial protein mutations in...

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Detalhes bibliográficos
Publicado no:Am J Med Genet A
Main Authors: Shehata, Bahig M., Lee, Kevin, Sabharwal, Ankit, Lalwani, Mukesh Kumar, Cundiff, Caitlin A., Davis, Angela K., Agarwal, Vartika, Sivasubbu, Sridhar, Gibson, Greg
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4753789/
https://ncbi.nlm.nih.gov/pubmed/25921236
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ajmg.a.37138
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