Mutations of the functional ARH1 allele in tumors from ARH1 heterozygous mice and cells affect ARH1 catalytic activity, cell proliferation and tumorigenesis

ADP-ribosylation results from transfer of the ADP-ribose moiety of nicotinamide adenine dinucleotide (NAD) to an acceptor with ADP-ribose-acceptor content determined by the activities of ADP-ribosyltransferases, which modify the acceptor, and ADP-ribose-acceptor hydrolase (ARH), which cleave the ADP...

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Detalhes bibliográficos
Publicado no:Oncogenesis
Main Authors: Kato, J, Vekhter, D, Heath, J, Zhu, J, Barbieri, J T, Moss, J
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
Assuntos:
Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4753525/
https://ncbi.nlm.nih.gov/pubmed/26029825
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/oncsis.2015.5
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