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Molecularly targeted therapy for advanced hepatocellular carcinoma - a drug development crisis?
Hepatocellular carcinoma is the fastest growing cause of cancer related death globally. Sorafenib, a multi-targeted kinase inhibitor, is the only drug proven to improve outcomes in patients with advanced disease offering modest survival benefit. Although comprehensive genomic mapping has improved un...
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| 發表在: | World J Gastrointest Oncol |
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| Main Authors: | , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Baishideng Publishing Group Inc
2016
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4753168/ https://ncbi.nlm.nih.gov/pubmed/26909132 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4251/wjgo.v8.i2.173 |
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