Effect of Colchicine on Platelet-Platelet and Platelet-Leukocyte Interactions: A Pilot Study in Healthy Subjects

The cardioprotective mechanisms of colchicine in patients with stable ischemic heart disease remain uncertain. We tested varying concentrations of colchicine on platelet activity in vitro, and a clinically relevant 1.8 mg oral loading dose administered over one hour in 10 healthy subjects. Data are...

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Gepubliceerd in:Inflammation
Hoofdauteurs: Shah, Binita, Allen, Nicole, Harchandani, Bhisham, Pillinger, Michael, Katz, Stuart, Sedlis, Steven P., Echagarruga, Christina, Samuels, Svetlana Krasnokutsky, Morina, Pajazit, Singh, Prabhjot, Karotkin, Liza, Berger, Jeffrey S.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2016
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4753094/
https://ncbi.nlm.nih.gov/pubmed/26318864
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10753-015-0237-7
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