Association of the OPRM1 variant rs1799971 (A118G) with non-specific liability to substance dependence in a collaborative de novo meta-analysis of European-ancestry cohorts

The mu1 opioid receptor gene, OPRM1, has long been a high-priority candidate for human genetic studies of addiction. Because of its potential functional significance, the non-synonymous variant rs1799971 (A118G, Asn40Asp) in OPRM1 has been extensively studied, yet its role in addiction has remained...

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Udgivet i:Behav Genet
Main Authors: Schwantes-An, Tae-Hwi, Zhang, Juan, Chen, Li-Shiun, Hartz, Sarah M., Culverhouse, Robert C., Chen, Xiangning, Coon, Hilary, Frank, Josef, Kamens, Helen M., Konte, Bettina, Kovanen, Leena, Latvala, Antti, Legrand, Lisa N., Maher, Brion S., Melroy, Whitney E., Nelson, Elliot C., Reid, Mark W., Robinson, Jason D., Shen, Pei-Hong, Yang, Bao-Zhu, Andrews, Judy A., Aveyard, Paul, Beltcheva, Olga, Brown, Sandra A., Cannon, Dale S., Cichon, Sven, Corley, Robin P., Dahmen, Norbert, Degenhardt, Louisa, Foroud, Tatiana, Gaebel, Wolfgang, Giegling, Ina, Glatt, Stephen J., Grucza, Richard A., Hardin, Jill, Hartmann, Annette M., Heath, Andrew C., Herms, Stefan, Hodgkinson, Colin A., Hoffmann, Per, Hops, Hyman, Huizinga, David, Ising, Marcus, Johnson, Eric O., Johnstone, Elaine, Kaneva, Radka P., Kendler, Kenneth S., Kiefer, Falk, Kranzler, Henry R., Krauter, Ken S., Levran, Orna, Lucae, Susanne, Lynskey, Michael T., Maier, Wolfgang, Mann, Karl, Martin, Nicholas G., Mattheisen, Manuel, Montgomery, Grant W., Müller-Myhsok, Bertram, Murphy, Michael F., Neale, Michael C., Nikolov, Momchil A., Nishita, Denise, Nöthen, Markus M, Nurnberger, John, Partonen, Timo, Pergadia, Michele L., Reynolds, Maureen, Ridinger, Monika, Rose, Richard J., Rouvinen-Lagerström, Noora, Scherbaum, Norbert, Schmäl, Christine, Soyka, Michael, Stallings, Michael C., Steffens, Michael, Treutlein, Jens, Tsuang, Ming, Wall, Tamara L., Wodarz, Norbert, Yuferov, Vadim, Zill, Peter, Bergen, Andrew W., Chen, Jingchun, Cinciripini, Paul M., Edenberg, Howard J, Ehringer, Marissa A., Ferrell, Robert E., Gelernter, Joel, Goldman, David, Hewitt, John K., Hopfer, Christian J., Iacono, William G., Kaprio, Jaakko, Kreek, Mary Jeanne, Kremensky, Ivo M., Madden, Pamela A.F., McGue, Matt, Munafò, Marcus R., Philibert, Robert A., Rietschel, Marcella, Roy, Alec, Rujescu, Dan, Saarikoski, Sirkku T., Swan, Gary E., Todorov, Alexandre A., Vanyukov, Michael M., Weiss, Robert B., Bierut, Laura J., Saccone, Nancy L.
Format: Artigo
Sprog:Inglês
Udgivet: 2015
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4752855/
https://ncbi.nlm.nih.gov/pubmed/26392368
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10519-015-9737-3
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