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The matching quality of experimental and control interventions in blinded pharmacological randomised clinical trials: a methodological systematic review

BACKGROUND: Blinding is a pivotal method to avoid bias in randomised clinical trials. In blinded drug trials, experimental and control interventions are often designed to be matched, i.e. to appear indistinguishable. It is unknown how often matching procedures are inadequate, so we decided to system...

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Bibliografiske detaljer
Udgivet i:BMC Med Res Methodol
Main Authors: Bello, Segun, Wei, Maoling, Hilden, Jørgen, Hróbjartsson, Asbjørn
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4752749/
https://ncbi.nlm.nih.gov/pubmed/26873063
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12874-016-0111-9
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