Low Vitamin-D Levels Combined with PKP3-SIGIRR-TMEM16J Host Variants Is Associated with Tuberculosis and Death in HIV-Infected and -Exposed Infants

BACKGROUND: This study examined the associations of 25-hydroxyvitamin D and specific host genetic variants that affect vitamin D levels or its effects on immune function, with the risk of TB or mortality in children. METHODS: A case-cohort sample of 466 South African infants enrolled in P1041 trial...

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Veröffentlicht in:PLoS One
Hauptverfasser: Gupta, Amita, Montepiedra, Grace, Gupte, Akshay, Zeldow, Bret, Jubulis, Jennifer, Detrick, Barbara, Violari, Avy, Madhi, Shabir, Bobat, Raziya, Cotton, Mark, Mitchell, Charles, Spector, Stephen
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2016
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Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4752266/
https://ncbi.nlm.nih.gov/pubmed/26872154
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0148649
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