IL-17RA in Non-Hematopoietic Cells Controls CXCL-1 and 5 Critical to Recruit Neutrophils to the Lung of Mycobacteria-Infected Mice during the Adaptive Immune Response

During chronic infection with Mycobacterium tuberculosis (Mtb), bacilli multiplication is constrained within lung granulomas until excessive inflammation destroys the lung. Neutrophils are recruited early and participate in granuloma formation, but excessive neutrophilia exacerbates the tuberculosis...

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Udgivet i:PLoS One
Main Authors: Lombard, Robin, Doz, Emilie, Carreras, Florence, Epardaud, Mathieu, Le Vern, Yves, Buzoni-Gatel, Dominique, Winter, Nathalie
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2016
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4752258/
https://ncbi.nlm.nih.gov/pubmed/26871571
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0149455
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