Serum Leukocyte Immunoglobulin-Like Receptor A3 (LILRA3) Is Increased in Patients with Multiple Sclerosis and Is a Strong Independent Indicator of Disease Severity; 6.7kbp LILRA3 Gene Deletion Is Not Associated with Diseases Susceptibility

Leukocyte immunoglobulin-like receptor A3 (LILRA3) is a soluble immune regulatory molecule primarily expressed by monocytes and macrophages. A homozygous 6.7kbp LILRA3 gene deletion that removes the first seven of its eight exons is predicted to lead to lack of LILRA3 protein, although this has not...

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Udgivet i:PLoS One
Main Authors: An, Hongyan, Lim, Chai, Guillemin, Gilles J., Vollmer-Conna, Ute, Rawlinson, William, Bryant, Katherine, Tedla, Nicodemus
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2016
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4752247/
https://ncbi.nlm.nih.gov/pubmed/26871720
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0149200
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