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Increased Frequency of T Follicular Helper Cells and Elevated Interleukin-27 Plasma Levels in Patients with Pemphigus

Pemphigus is an autoimmune disease in which IgG auto-antibodies (auto-ab) against the desmosomal cadherins desmoglein (Dsg) 3 and Dsg1 cause loss of epidermal keratinocyte adhesion. Aim of this study was to investigate cytokines derived from antigen-presenting cells (APC) and their relation to CD4(+...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Hennerici, Tina, Pollmann, Robert, Schmidt, Thomas, Seipelt, Maria, Tackenberg, Björn, Möbs, Christian, Ghoreschi, Kamran, Hertl, Michael, Eming, Rüdiger
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4752242/
https://ncbi.nlm.nih.gov/pubmed/26872212
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0148919
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