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Positive Selection or Free to Vary? Assessing the Functional Significance of Sequence Change Using Molecular Dynamics

Evolutionary arms races between pathogens and their hosts may be manifested as selection for rapid evolutionary change of key genes, and are sometimes detectable through sequence-level analyses. In the case of protein-coding genes, such analyses frequently predict that specific codons are under posi...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Allison, Jane R., Lechner, Marcus, Hoeppner, Marc P., Poole, Anthony M.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4752228/
https://ncbi.nlm.nih.gov/pubmed/26871901
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0147619
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