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Feeling the Squeeze: Live-Cell Extrusion Limits Cell Density in Epithelia

Tissues develop in confined volumes that can impose mechanical constraints on their growth, but it is unclear how cells respond to these limits to regulate tissue size and shape. Two papers show that overcrowding and cell deformation lead to the shedding of live cells to maintain homeostasis in epit...

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Detalhes bibliográficos
Publicado no:Cell
Main Authors: Fernandez-Gonzalez, Rodrigo, Zallen, Jennifer A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4752205/
https://ncbi.nlm.nih.gov/pubmed/22632965
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2012.05.006
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