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Mixing Apples and Oranges: Analysis of Heterotropic Cooperativity in Cytochrome P450 3A4
Heterotropic cooperative phenomena have been documented in studies with cytochrome P450 3A4, with few attempts to quantify this behavior other than to show the apparent stimulatory effect of certain CYP3A4 substrates on the enzyme’s catalytic activity for others. Here CYP3A4 solubilized in Nanodiscs...
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| Veröffentlicht in: | Arch Biochem Biophys |
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| Hauptverfasser: | , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2009
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4752175/ https://ncbi.nlm.nih.gov/pubmed/19560436 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.abb.2009.06.013 |
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