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Whole Genome Shotgun Sequencing Shows Selection on Leptospira Regulatory Proteins during in vitro Culture Attenuation

Leptospirosis is the most common zoonotic disease worldwide with an estimated 500,000 severe cases reported annually, and case fatality rates of 12–25%, due primarily to acute kidney and lung injuries. Despite its prevalence, the molecular mechanisms underlying leptospirosis pathogenesis remain poor...

詳細記述

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書誌詳細
出版年:Am J Trop Med Hyg
主要な著者: Lehmann, Jason S., Corey, Victoria C., Ricaldi, Jessica N., Vinetz, Joseph M., Winzeler, Elizabeth A., Matthias, Michael A.
フォーマット: Artigo
言語:Inglês
出版事項: The American Society of Tropical Medicine and Hygiene 2016
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4751964/
https://ncbi.nlm.nih.gov/pubmed/26711524
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4269/ajtmh.15-0401
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