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Shp2 Associates with and Enhances Nephrin Tyrosine Phosphorylation and Is Necessary for Foot Process Spreading in Mouse Models of Podocyte Injury

In most forms of glomerular diseases, loss of size selectivity by the kidney filtration barrier is associated with changes in the morphology of podocytes. The kidney filtration barrier is comprised of the endothelial lining, the glomerular basement membrane, and the podocyte intercellular junction,...

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Detalhes bibliográficos
Publicado no:Mol Cell Biol
Main Authors: Verma, Rakesh, Venkatareddy, Madhusudan, Kalinowski, Anne, Patel, Sanjeevkumar R., Salant, David J., Garg, Puneet
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4751697/
https://ncbi.nlm.nih.gov/pubmed/26644409
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00956-15
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