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LARP4 Is Regulated by Tumor Necrosis Factor Alpha in a Tristetraprolin-Dependent Manner

LARP4 is a protein with unknown function that independently binds to poly(A) RNA, RACK1, and the poly(A)-binding protein (PABPC1). Here, we report on its regulation. We found a conserved AU-rich element (ARE) in the human LARP4 mRNA 3′ untranslated region (UTR). This ARE, but not its antisense versi...

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Veröffentlicht in:Mol Cell Biol
Hauptverfasser: Mattijssen, Sandy, Maraia, Richard J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2016
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4751689/
https://ncbi.nlm.nih.gov/pubmed/26644407
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00804-15
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