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Discovery of candidate genes for nonsyndromic cleft lip palate through genome-wide linkage analysis of large extended families in the Malay population

BACKGROUND: Nonsyndromic orofacial clefts are one of the most common birth defects worldwide. It occurs as a result of genetic or environmental factors. This study investigates the genetic contribution to nonsyndromic cleft lip and/or palate through the analysis of family pedigrees. Candidate genes...

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Détails bibliographiques
Publié dans:BMC Genet
Auteurs principaux: Mohamad Shah, Nurul Syazana, Salahshourifar, Iman, Sulong, Sarina, Wan Sulaiman, Wan Azman, Halim, Ahmad Sukari
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2016
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4751652/
https://ncbi.nlm.nih.gov/pubmed/26868259
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12863-016-0345-x
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