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hnRNP-Q1 represses nascent axon growth in cortical neurons by inhibiting Gap-43 mRNA translation

Posttranscriptional regulation of gene expression by mRNA-binding proteins is critical for neuronal development and function. hnRNP-Q1 is an mRNA-binding protein that regulates mRNA processing events, including translational repression. hnRNP-Q1 is highly expressed in brain tissue, suggesting a func...

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Vydáno v:Mol Biol Cell
Hlavní autoři: Williams, Kathryn R., McAninch, Damian S., Stefanovic, Snezana, Xing, Lei, Allen, Megan, Li, Wenqi, Feng, Yue, Mihailescu, Mihaela Rita, Bassell, Gary J.
Médium: Artigo
Jazyk:Inglês
Vydáno: The American Society for Cell Biology 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4751602/
https://ncbi.nlm.nih.gov/pubmed/26658614
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E15-07-0504
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