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Aldose reductase participates in the downregulation of T cell functions due to suppressor macrophages
The cell-to-cell contact of T lymphocytes with immunosuppressive macrophages causes marked changes in the tyrosine phosphorylation of some cytosolic proteins of T cells. By phosphoproteome analysis, we identified a 36-kDa protein as aldose reductase (AR). The AR expression in T cells was not changed...
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| Publicado en: | Sci Rep |
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| Autores principales: | , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Nature Publishing Group
2016
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4751572/ https://ncbi.nlm.nih.gov/pubmed/26868163 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep21093 |
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