Cellular Senescence as the Causal Nexus of Aging

In this paper we present cellular senescence as the ultimate driver of the aging process, as a “causal nexus” that bridges microscopic subcellular damage with the phenotypic, macroscopic effect of aging. It is important to understand how the various types of subcellular damage correlated with the ag...

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Udgivet i:Front Genet
Main Authors: Bhatia-Dey, Naina, Kanherkar, Riya R., Stair, Susan E., Makarev, Evgeny O., Csoka, Antonei B.
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2016
Fag:
Genetics
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4751276/
https://ncbi.nlm.nih.gov/pubmed/26904101
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2016.00013
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