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The Impact of Saturable Metabolism on Exposure-Response Relations in 2 Studies of Benzene-induced Leukemia

Enzymatic saturation of metabolic pathways is one factor that potentially contributes to the nonlinear exposure-response relations that are frequently reported in occupational epidemiologic studies. The authors propose an approach to explore the contribution of saturable metabolism to previously rep...

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Опубликовано в: :Am J Epidemiol
Главные авторы: Vlaanderen, Jelle, Portengen, Lützen, Rappaport, Stephen M., Glass, Deborah C., Kromhout, Hans, Vermeulen, Roel
Формат: Artigo
Язык:Inglês
Опубликовано: Oxford University Press 2011
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4751240/
https://ncbi.nlm.nih.gov/pubmed/21745798
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/aje/kwr118
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