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A MARKOV RANDOM FIELD-BASED APPROACH TO CHARACTERIZING HUMAN BRAIN DEVELOPMENT USING SPATIAL–TEMPORAL TRANSCRIPTOME DATA()

Human neurodevelopment is a highly regulated biological process. In this article, we study the dynamic changes of neurodevelopment through the analysis of human brain microarray data, sampled from 16 brain regions in 15 time periods of neurodevelopment. We develop a two-step inferential procedure to...

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Detalhes bibliográficos
Publicado no:Ann Appl Stat
Main Authors: Lin, Zhixiang, Sanders, Stephan J., Li, Mingfeng, Sestan, Nenad, State, Matthew W., Zhao, Hongyu
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4751044/
https://ncbi.nlm.nih.gov/pubmed/26877824
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1214/14-AOAS802
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