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Origin of stem cells in the BM niche: new clues from mastocytosis

In this issue of Blood, Garcia-Montero et al(1) reported that in nearly 30% of patients with indolent systemic mastocytosis (SM), the characteristic c-kit mutation D816V,(2) is not restricted to mast cells, but may also be found in bone marrow (BM)–derived mesenchymal stem cells (MSCs), also known a...

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Pubblicato in:Blood
Autori principali: Nemeth, Krisztian, Mezey, Eva
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society of Hematology 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4751020/
https://ncbi.nlm.nih.gov/pubmed/26869307
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2015-12-686626
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