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Quantitative In Silico analysis of transient metabolism of acetaminophen and associated causes of hepatotoxicity in humans
PURPOSE: Although safe at therapeutic levels, excess intake of acetaminophen can lead to hepatic injury or acute liver failure (ALF). A number of different factors influence metabolism and hepatotoxicity of acetaminophen in patients. Three of the most important are a patient’s physiological response...
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| Publicado no: | In Silico Pharmacol |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Springer Berlin Heidelberg
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4750864/ https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2193-9616-1-14 |
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