Preliminary safety, pharmacokinetics, and efficacy of regorafenib, cisplatin, and pemetrexed in patients with advanced non-squamous non-small cell lung cancers

PURPOSE: The addition of bevacizumab, an anti-angiogenesis agent, to cytotoxic chemotherapy improves survival in patients with advanced non-squamous non-small cell lung cancers (nsNSCLCs). Regorafenib is an oral multi-targeted kinase inhibitor with potent anti-angiogenic activity that is approved fo...

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Detalhes bibliográficos
Publicado no:Clin Lung Cancer
Main Authors: Hellmann, Matthew D, Sturm, Isrid, Trnkova, Zuzana Jirakova, Lettieri, John, Diefenbach, Konstanze, Rizvi, Naiyer A., Gettinger, Scott N.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4750397/
https://ncbi.nlm.nih.gov/pubmed/26003007
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cllc.2015.04.003
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