Progranulin Reduced Neuronal Cell Death by Activation of Sortilin 1 Signaling Pathways After Subarachnoid Hemorrhage in Rats

OBJECTIVES: Progranulin has been reported to have neuroprotective actions in cultured neurons. This study investigated the effect of recombinant rat progranulin on early brain injury after subarachnoid hemorrhage. DESIGN: Controlled in vivo laboratory study. SETTING: Animal research laboratory. SUBJ...

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Bibliografiske detaljer
Udgivet i:Crit Care Med
Main Authors: Li, Bo, He, Yue, Xu, Liang, Hu, Qin, Tang, Junjia, Chen, Yujie, Tang, Jiping, Feng, Hua, Zhang, John H.
Format: Artigo
Sprog:Inglês
Udgivet: 2015
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4750384/
https://ncbi.nlm.nih.gov/pubmed/26010686
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/CCM.0000000000001096
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