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Strain-transcending immune response generated by chimeras of the malaria vaccine candidate merozoite surface protein 2

MSP2 is an intrinsically disordered protein that is abundant on the merozoite surface and essential to the parasite Plasmodium falciparum. Naturally-acquired antibody responses to MSP2 are biased towards dimorphic sequences within the central variable region of MSP2 and have been linked to naturally...

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Bibliografiske detaljer
Udgivet i:Sci Rep
Main Authors: Krishnarjuna, Bankala, Andrew, Dean, MacRaild, Christopher A., Morales, Rodrigo A. V., Beeson, James G., Anders, Robin F., Richards, Jack S., Norton, Raymond S.
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4749986/
https://ncbi.nlm.nih.gov/pubmed/26865062
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep20613
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