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Intrinsic and membrane-facilitated α-synuclein oligomerization revealed by label-free detection through solid-state nanopores

α-Synuclein (α-Syn) is an abundant cytosolic protein involved in the release of neurotransmitters in presynaptic terminal and its aberrant aggregation is found to be associated with Parkinson’s disease. Recent study suggests that the oligomers formed at the initial oligomerization stage may be the r...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Sci Rep
Egile Nagusiak: Hu, Rui, Diao, Jiajie, Li, Ji, Tang, Zhipeng, Li, Xiaoqing, Leitz, Jeremy, Long, Jiangang, Liu, Jiankang, Yu, Dapeng, Zhao, Qing
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Nature Publishing Group 2016
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4749980/
https://ncbi.nlm.nih.gov/pubmed/26865505
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep20776
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