Nanocaged enzymes with enhanced catalytic activity and increased stability against protease digestion

Cells routinely compartmentalize enzymes for enhanced efficiency of their metabolic pathways. Here we report a general approach to construct DNA nanocaged enzymes for enhancing catalytic activity and stability. Nanocaged enzymes are realized by self-assembly into DNA nanocages with well-controlled s...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Zhao, Zhao, Fu, Jinglin, Dhakal, Soma, Johnson-Buck, Alexander, Liu, Minghui, Zhang, Ting, Woodbury, Neal W., Liu, Yan, Walter, Nils G., Yan, Hao
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4749968/
https://ncbi.nlm.nih.gov/pubmed/26861509
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms10619
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