Th17 Cells Pathways in Multiple Sclerosis and Neuromyelitis Optica Spectrum Disorders: Pathophysiological and Therapeutic Implications

Several animal and human studies have implicated CD4+ T helper 17 (Th17) cells and their downstream pathways in the pathogenesis of central nervous system (CNS) autoimmunity in multiple sclerosis (MS) and neuromyelitis optica spectrum disorders (NMOSD), challenging the traditional Th1-Th2 paradigm....

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Bibliographische Detailangaben
Veröffentlicht in:Mediators Inflamm
Hauptverfasser: Passos, Giordani Rodrigues Dos, Sato, Douglas Kazutoshi, Becker, Jefferson, Fujihara, Kazuo
Format: Artigo
Sprache:Inglês
Veröffentlicht: Hindawi Publishing Corporation 2016
Schlagworte:
Review Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4749822/
https://ncbi.nlm.nih.gov/pubmed/26941483
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2016/5314541
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