Pdgfrβ+ Mural Preadipocytes Contribute to Adipocyte Hyperplasia Induced by High-Fat Diet Feeding and Prolonged Cold Exposure in Adult Mice

The expansion of white adipose tissue (WAT) in obesity involves de novo differentiation of new adipocytes; however, the cellular origin of these cells remains unclear. Here, we utilize Zfp423(GFP) reporter mice to characterize adipose mural (Pdgfrβ(+)) cells with varying levels of the preadipocyte c...

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Pubblicato in:Cell Metab
Autori principali: Vishvanath, Lavanya, MacPherson, Karen A., Hepler, Chelsea, Wang, Qiong A., Shao, Mengle, Spurgin, Stephen B., Wang, Margaret Y., Kusminski, Christine M., Morley, Thomas S., Gupta, Rana K.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2015
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4749445/
https://ncbi.nlm.nih.gov/pubmed/26626462
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2015.10.018
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