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A chromatin folding model that incorporates linker variability generates fibers resembling the native structures.

The "30-nm" chromatin fibers, as observed in eukaryotic nuclei, are considered a discrete level in a hierarchy of DNA folding. At present, there is considerable debate as to how the nucleosomes and linker DNA are organized within chromatin fibers, and a number of models have been proposed, many of w...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Principais autores: Woodcock, C L, Grigoryev, S A, Horowitz, R A, Whitaker, N
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1993
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC47493/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8415647/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.90.19.9021
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