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Interferon-γ Is a Crucial Activator of Early Host Immune Defense against Mycobacterium ulcerans Infection in Mice

Buruli ulcer (BU), caused by infection with Mycobacterium ulcerans, is a chronic necrotizing human skin disease associated with the production of the cytotoxic macrolide exotoxin mycolactone. Despite extensive research, the type of immune responses elicited against this pathogen and the effector fun...

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Dettagli Bibliografici
Pubblicato in:PLoS Negl Trop Dis
Autori principali: Bieri, Raphael, Bolz, Miriam, Ruf, Marie-Thérèse, Pluschke, Gerd
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4749296/
https://ncbi.nlm.nih.gov/pubmed/26863011
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0004450
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