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Synergistic Effect of Anti-Angiogenic and Radiation Therapy: Quantitative Evaluation with Dynamic Contrast Enhanced MR Imaging

PURPOSE: We assessed the effects of anti-angiogenic therapy (AAT) on radiation therapy (RT), evaluating the tumor growth and perfusion patterns on dynamic contrast enhanced MR (DCE-MR) images. METHODS: Thirteen nude mice with heterotopic xenograft cancer of human lung cancer cell line were used. To...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Koo, Hyun Jung, Lee, Myoungsun, Kim, Jin, Woo, Chul Woong, Jeong, Seong-Yun, Choi, Eun Kyung, Kim, Namkug, Lee, Jin Seong
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4749295/
https://ncbi.nlm.nih.gov/pubmed/26862906
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0148784
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