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The transcriptional control of the perforin locus
Natural killer (NK) cells and cytotoxic T lymphocytes (CTL) use cytotoxic granules containing perforin and granzymes to lyse infected or malignant host cells and provide immunity to intracellular microbes and tumors. Perforin is essential for cytotoxic granule-mediated killing. Perforin expression i...
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| Publicado no: | Immunol Rev |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4749266/ https://ncbi.nlm.nih.gov/pubmed/20536555 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.0105-2896.2010.00905.x |
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